In recent years, the Sagalassos Archaeological Research project of the University of Leuven has coordinated a research programme aimed at the community of ancient Sagalassos. Understanding in more detail how the ordinary townsfolk lived and worked in antiquity forms an important aspect of this research. With this aim in mind, archaeological excavations were launched at Site LE in 2012. Here, a dense stratigraphical sequence documenting changes within part of a neighbourhood in the upper parts of the ancient town was documented. An original domestic quarter changed character resulting from the erection of public buildings in Roman Imperial times, such as the Neon Library and the unidentified public building of Site LE. In late Roman times, the structures of Site LE were thoroughly re-organized, possibly including a house and a textile workshop. A very well preserved coroplast workshop formed part of this arrangement too. Upon abandonment of these domestic and artisanal units, Site LE was overhauled one last time. Remains of an early Byzantine professional bakery were identified within the re-organized premises. This paper wishes to present our initial understanding of the site, its phases of architectural and functional organisation as well as the detail of the consecutive structures. As such, the paper represents the framework for continued study and future publication of the at times fairly unique find assemblages, such as the materials found within the late Roman coroplast workshop.