Palmitate activates insulin signaling pathway in pancreatic rat islets
Graciano, Maria Fernanda R Nogueira, Tatiane C Carvalho, Carla R O Curi, Rui Carpinelli, Angelo R # ×
Pancreas vol:38 issue:5 pages:578-84
To investigate the action of palmitate on insulin receptor (IR) signaling pathway in rat pancreatic islets. The following proteins were studied: IR substrate-1 and -2 (IRS1 and IRS2), phosphatidylinositol 3-kinase, extracellular signal-regulated protein kinase-1 and -2 (ERK1/2), and signal transducer and activator of transcription 3 (STAT3).