Title: Gastrointestinal transfer: in vivo evaluation and implementation in in vitro and in silico predictive tools
Authors: Hens, Bart ×
Brouwers, Joachim
Anneveld, Bart
Corsetti, Maura
Symillides, Mira
Vertzoni, Maria
Reppas, Christos
Turner, David B
Augustijns, Patrick #
Issue Date: Oct-2014
Publisher: Elsevier
Series Title: European Journal of Pharmaceutical Sciences vol:63 pages:233-42
Article number: 10.1016/j.ejps.2014.07.008
Abstract: The purpose of this study was to explore the transfer of drug solutions from stomach to small intestine and its impact on intraluminal drug concentrations in humans. The collected intraluminal data were used as reference to evaluate simulations of gastrointestinal transfer currently implemented in different in vitro and in silico absorption models.
ISSN: 0928-0987
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Drug Delivery and Disposition
Translational Research in GastroIntestinal Disorders
× corresponding author
# (joint) last author

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