Title: Cutaneous reflex modulation and self-induced reflex attenuation in cerebellar patients
Authors: Hoogkamer, Wouter ×
Van Calenbergh, Frank
Swinnen, Stephan
Duysens, Jaak #
Issue Date: 1-Feb-2015
Publisher: The Society
Series Title: Journal of Neurophysiology vol:113 pages:915-924
Article number: 10.1152/jn.00381.2014
Abstract: Modulation of cutaneous reflexes is important in the neural control of walking, yet knowledge about underlying neural pathways is still incomplete. Recent studies have suggested that the cerebellum is involved. Here, we evaluated the possible roles of the cerebellum in cutaneous reflex modulation and in attenuation of self-induced reflexes. First it was checked whether leg muscle activity during walking was similar both in patients with focal cerebellar lesions and in healthy controls. We then recorded cutaneous reflex activity in leg muscles during walking. Additionally, we compared reflexes after standard (computer-triggered) stimuli with reflexes after self-induced stimuli for both groups. Biceps femoris and gastrocnemius medialis muscle activity was increased in the patient group compared to the controls, suggesting a co-activation strategy to reduce instability of gait. Cutaneous reflex modulation was similar between healthy controls and cerebellar patients, but the latter appeared less able to attenuate reflexes to self-induced stimuli. This suggests that the cerebellum is not primarily involved in cutaneous reflex modulation but that it could act in attenuation of self-induced reflex responses. The latter role in locomotion would be consistent with the common view that the cerebellum predicts sensory consequences of movement.
ISSN: 0022-3077
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Movement Control & Neuroplasticity Research Group
Research Group Experimental Neurosurgery and Neuroanatomy
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science