Title: Does blood pressure variability contribute to risk stratification? Methodological issues and a review of outcome studies based on home blood pressure
Authors: Asayama, Kei ×
Wei, Fangfei
Liu, Yanping
Hara, Azusa
Gu, Yumei
Schutte, Rudolph
Li, Yan
Thijs, Lutgarde
Staessen, Jan A #
Issue Date: Feb-2015
Publisher: The Society
Series Title: Hypertension Research vol:38 issue:2 pages:97-101
Article number: 10.1038/hr.2014.153
Abstract: This review addresses methodological issues in the assessment of blood pressure variability and the predictive value of blood pressure variability derived from blood pressure readings obtained in the relaxed home environment. Preference should be given to indexes of blood pressure variability that are independent of the mean because we should evaluate the impact of blood pressure variability by eliminating the effect of blood pressure levels. Beat-to-beat blood pressure recordings outperform home blood pressure measurement in the assessment of blood pressure variability in longitudinal Belgian and Japanese population studies, whereas blood pressure variability did not incrementally predict outcome beyond blood pressure level and other cardiovascular risk factors. In conclusion, clinicians should focus on blood pressure level, given that it is the predominant risk factor and is manageable by lifestyle modifications and adequate antihypertensive drug treatment. Blood pressure variability remains a research tool that requires further prospective studies with hard end points to define its potential application, as it may be potentially useful in daily clinical practice.Hypertension Research advance online publication, 16 October 2014; doi:10.1038/hr.2014.153.
ISSN: 0916-9636
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Department of Cardiovascular Sciences - miscellaneous
Hypertension and Cardiovascular Epidemiology
× corresponding author
# (joint) last author

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