Unique Tracheal Fluid MicroRNA Signature Predicts Response to FETO in Patients With Congenital Diaphragmatic Hernia
Pereira-Terra, Patrícia × Deprest, Jan Kholdebarin, Ramin Khoshgoo, Naghmeh DeKoninck, Philip Boerema-De Munck, Anne A Wang, Jinxia Zhu, Fuqin Rottier, Robbert J Iwasiow, Barbara M Correia-Pinto, Jorge Tibboel, Dick Post, Martin Keijzer, Richard #
Lippincott, Williams & Wilkins
Annals of Surgery vol:262 issue:6 pages:1130-40
Our objective was to determine the fetal in vivo microRNA signature in hypoplastic lungs of human fetuses with severe isolated congenital diaphragmatic hernia (CDH) and changes in tracheal and amniotic fluid of fetuses undergoing fetoscopic endoluminal tracheal occlusion (FETO) to reverse severe lung hypoplasia due to CDH.