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Title: Age-specific differences between conventional and ambulatory daytime blood pressure values
Authors: Conen, David ×
Aeschbacher, Stefanie
Thijs, Lutgarde
Li, Yan
Boggia, José
Asayama, Kei
Hansen, Tine W
Kikuya, Masahiro
Björklund-Bodegård, Kristina
Ohkubo, Takayoshi
Jeppesen, Jørgen
Gu, Yu-Mei
Torp-Pedersen, Christian
Dolan, Eamon
Kuznetsova, Tatiana
Stolarz-Skrzypek, Katarzyna
Tikhonoff, Valérie
Schoen, Tobias
Malyutina, Sofia
Casiglia, Edoardo
Nikitin, Yuri
Lind, Lars
Sandoya, Edgardo
Kawecka-Jaszcz, Kalina
Mena, Luis
Maestre, Gladys E
Filipovský, Jan
Imai, Yutaka
O'Brien, Eoin
Wang, Ji-Guang
Risch, Lorenz
Staessen, Jan A #
Issue Date: Nov-2014
Publisher: Lippincott Williams & Wilkins
Series Title: Hypertension vol:64 issue:5 pages:1073-9
Article number: 10.1161/HYPERTENSIONAHA.114.03957
Abstract: Mean daytime ambulatory blood pressure (BP) values are considered to be lower than conventional BP values, but data on this relation among younger individuals <50 years are scarce. Conventional and 24-hour ambulatory BP were measured in 9550 individuals not taking antihypertensive treatment from 13 population-based cohorts. We compared individual differences between daytime ambulatory and conventional BP according to 10-year age categories. Age-specific prevalences of white coat and masked hypertension were calculated. Among individuals aged 18 to 30, 30 to 40, and 40 to 50 years, mean daytime BP was significantly higher than the corresponding conventional BP (6.0, 5.2, and 4.7 mm Hg for systolic; 2.5, 2.7, and 1.7 mm Hg for diastolic BP; all P<0.0001). In individuals aged 60 to 70 and ≥70 years, conventional BP was significantly higher than daytime ambulatory BP (5.0 and 13.0 mm Hg for systolic; 2.0 and 4.2 mm Hg for diastolic BP; all P<0.0001).The prevalence of white coat hypertension exponentially increased from 2.2% to 19.5% from those aged 18 to 30 years to those aged ≥70 years, with little variation between men and women (8.0% versus 6.1%; P=0.0003). Masked hypertension was more prevalent among men (21.1% versus 11.4%; P<0.0001). The age-specific prevalences of masked hypertension were 18.2%, 27.3%, 27.8%, 20.1%, 13.6%, and 10.2% among men and 9.0%, 9.9%, 12.2%, 11.9%, 14.7%, and 12.1% among women. In conclusion, this large collaborative analysis showed that the relation between daytime ambulatory and conventional BP strongly varies by age. These findings may have implications for diagnosing hypertension and its subtypes in clinical practice.
ISSN: 0194-911X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Hypertension and Cardiovascular Epidemiology
Department of Cardiovascular Sciences - miscellaneous
× corresponding author
# (joint) last author

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