Title: The effect of forced exercise on knee joints in Dio2-/- mice: type II iodothyronine deiodinase-deficient mice are less prone to develop OA-like cartilage damage upon excessive mechanical stress
Authors: Bomer, Nils *
Cornelis, Frederique *
Ramos, Yolande Fm
den Hollander, Wouter
Storms, Lies
van der Breggen, Ruud
Lakenberg, Nico
Slagboom, P Eline
Meulenbelt, Ingrid
Lories, Rik # ×
Issue Date: Mar-2016
Publisher: H.K. Lewis
Series Title: Annals of the Rheumatic Diseases vol:75 issue:3 pages:571-7
Article number: annrheumdis-2014-206608
Abstract: To further explore deiodinase iodothyronine type 2 (DIO2) as a therapeutic target in osteoarthritis (OA) by studying the effects of forced mechanical loading on in vivo joint cartilage tissue homeostasis and the modulating effect herein of Dio2 deficiency.
ISSN: 0003-4967
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Skeletal Biology and Engineering Research Center (+)
* (joint) first author
× corresponding author
# (joint) last author

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