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Title: Osseous reconstruction using an occlusive titanium membrane following marginal mandibulectomy: proof of principle
Authors: Vrielinck, Luc ×
Sun, Yi
Schepers, Serge
Politis, Constantinus
Van Slycke, Sarah
Agbaje, Jimoh #
Issue Date: May-2014
Publisher: Lippincott Williams & Wilkins
Series Title: The Journal of Craniofacial Surgery vol:25 issue:3 pages:1112-4
Article number: 10.1097/SCS.0000000000000743
Abstract: Guided bone regeneration using barrier membranes is useful in bone augmentation. In contrast to flexible membranes, stiff membranes such as titanium membranes are capable of maintaining sufficient space underneath them. We report a case of bone regeneration under an occlusive titanium membrane following marginal mandibulectomy in a 50-year-old patient with odontogenic keratocyst. Preoperative analysis of the anatomical conditions was evaluated with panoramic radiographs and spiral computer tomography (CT) scan. The digital data from the CT scan were transferred to a personal computer. Using Simplant software, a mirror image of the right mandible was constructed from which a custom-made titanium membrane was made. The cyst with the remaining inferior alveolar nerve was removed and curettage of the lesion was performed under general anesthesia. The definitive titanium plate was inserted and fixated with osteosynthesis screws, and then removed 5 years later. Postoperative CT scanning showed good healing, bone growth under the titanium plate, and no evidence of residual cyst The titanium plate reinforced the mandibular skeleton and restored the shape of the mandible and facial symmetry; it also promoted new bone formation to fill in the mandibular defects.
ISSN: 1049-2275
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Oral and Maxillo-facial Surgery - Imaging & Pathology (OMFS-IMPATH)
× corresponding author
# (joint) last author

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