Title: Novel LC-MS/MS method for plasma vancomycin: Comparison with immunoassays and clinical impact
Authors: Oyaert, Matthijs ×
Peersman, Nele
Kieffer, Davy
Deiteren, Kathleen
Smits, Anne
Allegaert, Karel
Spriet, Isabel
Van Eldere, Johan
Verhaegen, Jan
Vermeersch, Pieter
Pauwels, Steven #
Issue Date: Feb-2015
Publisher: Elsevier Scientific Pub. Co.
Series Title: Clinica Chimica Acta vol:441 pages:63-70
Article number: S0009-8981(14)00546-4
Abstract: Accurate quantification of vancomycin in plasma is important for adequate dose-adjustment. As literature suggests between-method differences, our first objective was to develop a novel liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for total vancomycin in human plasma and to compare frequently used immunoassays with this method. Secondly, we investigated the clinical impact of between-method quantification differences.
ISSN: 0009-8981
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical Bacteriology and Mycology
Department of Microbiology & Immunology - miscellaneous
Organ Systems (+)
Clinical Pharmacology and Pharmacotherapy
× corresponding author
# (joint) last author

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