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Title: Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study
Authors: Lee, Alice W ×
Tyrer, Jonathan P
Doherty, Jennifer A
Stram, Douglas A
Kupryjanczyk, Jolanta
Dansonka-Mieszkowska, Agnieszka
Plisiecka-Halasa, Joanna
Spiewankiewicz, Beata
Myers, Emily J
Australian Cancer Study (Ovarian Cancer)
Australian Ovarian Cancer Study Group
Chenevix-Trench, Georgia
Fasching, Peter A
Beckmann, Matthias W
Ekici, Arif B
Hein, Alexander
Vergote, Ignace
Van Nieuwenhuysen, Els
Lambrechts, Diether
Wicklund, Kristine G
Eilber, Ursula
Wang-Gohrke, Shan
Chang-Claude, Jenny
Rudolph, Anja
Sucheston, Lara
Odunsi, Kunle
Moysich, Kirsten B
Shvetsov, Yurii B
Thompson, Pamela J
Goodman, Marc T
Wilkens, Lynne R
Dörk, Thilo
Hillemanns, Peter
Dürst, Matthias
Runnebaum, Ingo B
Bogdanova, Natalia
Pelttari, Liisa M
Nevanlinna, Heli
Leminen, Arto
Edwards, Robert P
Kelley, Joseph L
Harter, Philipp
Schwaab, Ira
Heitz, Florian
du Bois, Andreas
Orsulic, Sandra
Lester, Jenny
Walsh, Christine
Karlan, Beth Y
Hogdall, Estrid
Kjaer, Susanne K
Jensen, Allan
Vierkant, Robert A
Cunningham, Julie M
Goode, Ellen L
Fridley, Brooke L
Southey, Melissa C
Giles, Graham G
Bruinsma, Fiona
Wu, Xifeng
Hildebrandt, Michelle A T
Lu, Karen
Liang, Dong
Bisogna, Maria
Levine, Douglas A
Weber, Rachel Palmieri
Schildkraut, Joellen M
Iversen, Edwin S
Berchuck, Andrew
Terry, Kathryn L
Cramer, Daniel W
Tworoger, Shelley S
Poole, Elizabeth M
Olson, Sara H
Orlow, Irene
Bandera, Elisa V
Bjorge, Line
Tangen, Ingvild L
Salvesen, Helga B
Krakstad, Camilla
Massuger, Leon F A G
Kiemeney, Lambertus A
Aben, Katja K H
van Altena, Anne M
Bean, Yukie
Pejovic, Tanja
Kellar, Melissa
Le, Nhu D
Cook, Linda S
Kelemen, Linda E
Brooks-Wilson, Angela
Lubinski, Jan
Gronwald, Jacek
Cybulski, Cezary
Jakubowska, Anna
Wentzensen, Nicolas
Brinton, Louise A
Lissowska, Jolanta
Yang, Hannah
Nedergaard, Lotte
Lundvall, Lene
Hogdall, Claus
Song, Honglin
Campbell, Ian G
Eccles, Diana
Glasspool, Rosalind
Siddiqui, Nadeem
Carty, Karen
Paul, James
McNeish, Ian
Sieh, Weiva
McGuire, Valerie
Rothstein, Joseph H
Whittemore, Alice S
McLaughlin, John R
Risch, Harvey A
Phelan, Catherine M
Anton-Culver, Hoda
Ziogas, Argyrios
Menon, Usha
Ramus, Susan J
Gentry-Maharaj, Aleksandra
Harrington, Patricia
Pike, Malcolm C
Modugno, Francesmary
Rossing, Mary Anne
Ness, Roberta B
Pharoah, Paul D P
Stram, Daniel O
Wu, Anna H
Pearce, Celeste Leigh #
Issue Date: Mar-2015
Publisher: Academic Press
Series Title: Gynecologic Oncology vol:136 issue:3 pages:542-8
Article number: S0090-8258(14)01572-8
Abstract: Ovarian cancer is a hormone-related disease with a strong genetic basis. However, none of its high-penetrance susceptibility genes and GWAS-identified variants to date are known to be involved in hormonal pathways. Given the hypothesized etiologic role of gonadotropins, an assessment of how variability in genes involved in the gonadotropin signaling pathway impacts disease risk is warranted.
ISSN: 0090-8258
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Gynaecological Oncology
Laboratory of Translational Genetics (Vesalius Research Center) (+)
× corresponding author
# (joint) last author

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