Optical coherence tomography study of healing characteristics of paclitaxel-eluting balloons vs. everolimus-eluting stents for in-stent restenosis: the SEDUCE (Safety and Efficacy of a Drug elUting balloon in Coronary artery rEstenosis) randomised clinical trial

Adriaenssens, Tom; Dens, Joseph; Ughi, Giovanni; Bennett, Johannes; Dubois, Christophe; Sinnaeve, Peter; Wiyono, Stefanus; Coosemans, Mark; Belmans, Ann; D'hooge, Jan; Vrolix, Mathias; Desmet, Walter

doi:10.4244/EIJV10I4A77

Optical coherence tomography study of healing characteristics of paclitaxel-eluting balloons vs. everolimus-eluting stents for in-stent restenosis: the SEDUCE (Safety and Efficacy of a Drug elUting balloon in Coronary artery rEstenosis) randomised clinical trial

Author:

Adriaenssens, Tom

Dens, Joseph ; Ughi, Giovanni ; Bennett, Johannes ; Dubois, Christophe ; Sinnaeve, Peter ; Wiyono, Stefanus ; Coosemans, Mark ; Belmans, Ann ; D'hooge, Jan ; Vrolix, Mathias ; Desmet, Walter

Keywords:

drug-eluting balloon, drug-eluting stent, in-stent restenosis, optical coherence tomography, percutaneous coronary intervention, stent coverage, Science & Technology, Life Sciences & Biomedicine, Cardiac & Cardiovascular Systems, Cardiovascular System & Cardiology, BARE-METAL STENTS, COATED BALLOON, FOLLOW-UP, VASCULAR BRACHYTHERAPY, MYOCARDIAL-INFARCTION, NEOINTIMAL COVERAGE, ANGIOPLASTY, NEOATHEROSCLEROSIS, ANGIOGRAPHY, PREVENTION, Aged, Angioplasty, Balloon, Coronary, Cardiovascular Agents, Coronary Restenosis, Coronary Vessels, Drug-Eluting Stents, Everolimus, Female, Humans, Male, Middle Aged, Paclitaxel, Sirolimus, Tomography, Optical Coherence, Treatment Outcome, 0104 Statistics, 3201 Cardiovascular medicine and haematology

Abstract:

Little is known about the respective healing responses and clinical efficacy and safety of drug-eluting balloons (DEB) and the second generation of drug-eluting stents (DES) when used to treat in-stent restenosis (ISR). In this study, we set out to compare prospectively the healing characteristics, as assessed by optical coherence tomography (OCT), of DEB versus DES after treatment of ISR in bare metal stents (BMS).