Title: Differential inhibitory effects of Evans blue on various DNA polymerases
Authors: Nakane, H ×
Balzarini, Jan
De Clercq, Erik
Ono, K #
Issue Date: 1986
Publisher: Information Retrieval Ltd.
Series Title: Nucleic Acids Symposium Series issue:17 pages:183-6
Abstract: Evans Blue, an anionic dye which has been found to inhibit the replication of human immunodeficiency virus, proved also inhibitory to the DNA polymerases alpha and beta. The mode of inhibition was competitive with respect to the template X primer, and noncompetitive with respect to the deoxynucleoside triphosphate substrates. The inhibitory effect of Evans Blue on DNA polymerases is discussed in relation to that of suramin.
ISSN: 0261-3166
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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