Title: Experimental herpetic keratitis in rabbit corneal organ cultures
Authors: Percy, D H ×
Creighton, M O
Hatch, L A
De Clercq, Erik #
Issue Date: Feb-1984
Publisher: H.K. Lewis
Series Title: The British Journal of Experimental Pathology vol:65 issue:1 pages:41-9
Abstract: An in-vitro method for maintaining rabbit corneal organ cultures for short periods of time is described. These cultures supported replication of strains of type 1 and 2 herpes simplex virus, and changes typical of herpetic infections of the cornea in vivo were observed by light microscopy, and by scanning and transmission electron microscopy. Infectious virus was readily recovered from inoculated corneal organ cultures. For practical, economic and humanitarian reasons, the full potential of this system warrants further investigation.
ISSN: 0007-1021
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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