Title: Genetic markers of bevacizumab-induced hypertension
Authors: Lambrechts, Diether ×
Moisse, Matthieu
Delmar, Paul
Miles, David W
Leighl, Natasha
Escudier, Bernard
Van Cutsem, Eric
Bansal, Aruna T
Carmeliet, Peter
Scherer, Stefan J
de Haas, Sanne
Pallaud, Celine #
Issue Date: Jul-2014
Publisher: Rapid Science Publishers
Series Title: Angiogenesis vol:17 issue:3 pages:685-94
Article number: 10.1007/s10456-014-9424-7
Abstract: There are currently no validated biomarkers predicting bevacizumab treatment outcome or toxicity. We combined biomarker data from six phase III trials of bevacizumab to assess whether genetic variation in vascular endothelial growth factor-A (VEGF-A) pathway or hypertension-related genes are associated with bevacizumab-induced hypertension.
ISSN: 0969-6970
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Translational Genetics (Vesalius Research Center) (+)
Clinical Digestive Oncology (+)
Laboratory of Angiogenesis and Vascular Metabolism (VIB-KU Leuven Centre for Cancer Biology) (+)
× corresponding author
# (joint) last author

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