Title: The synthesis and properties of some 5-substituted uracil derivatives
Authors: Walker, R T ×
Jones, A S
Rahim, S G
Serafinowski, P
De Clercq, Erik #
Issue Date: 1981
Publisher: Information Retrieval Ltd.
Series Title: Nucleic Acids Symposium Series issue:9 pages:21-4
Abstract: The problems encountered in the synthesis of 5-vinyl-2'-deoxyuridine are outlined and the synthesis of 5-bromoethynyl-2'-deoxyuridine described. E-5-(2-Bromovinyl)-2'-deoxyuridine is the most potent and specific agent against some herpes viruses yet discovered; we have now synthesised the Z-isomer and this appears to be essentially biologically inert.
ISSN: 0261-3166
Publication status: published
KU Leuven publication type: IC
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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