Title: Antiviral activity of carbopol, a cross-linked polycarboxylate
Authors: De Clercq, Erik ×
Luczak, M #
Issue Date: 1976
Publisher: Springer-Verlag
Series Title: Archives of Virology vol:52 issue:1-2 pages:151-8
Abstract: Carbopol, a polymer of acrylic acid cross-linked with allylsucrose, was found to impart resistance to virus infection in mice which received an intraperitoneal injection of the polycarboxylate 1 or 4 days before either intravenous vaccinia virus challenge or intranasal herpes simplex virus challenge. An interferon-like substance was detected in the blood stream 20-40 hours after the intraperitoneal injection of carbopol. The antiviral activity of this cross-linked polycarboxylate could be due to activation of peritoneal macrophages and/or interferon production.
ISSN: 0304-8608
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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