Prevalence of BRCA-1 associated protein 1 germline mutation in sporadic malignant pleural mesothelioma cases
Rusch, Andreas × Ziltener, Gabriela Nackaerts, Kristiaan Weder, Walter Stahel, Rolf A Felley-Bosco, Emanuela #
Lung Cancer vol:87 issue:1 pages:77-9
23% of mesothelioma tumor specimens have a mutation in the BRCA1-associated protein 1 (BAP1) gene and germline BAP1 mutations predispose to malignant pleural mesothelioma (MPM). Our aim was to investigate germline BAP1 mutations in sporadic MPM patients.