Title: The associations between pre-existing mental disorders and subsequent onset of chronic headaches: A worldwide epidemiological perspective
Authors: Bruffaerts, Ronny ×
Demyttenaere, Koen
Kessler, Ronald C
Tachimori, Hisateru
Bunting, Brendan
Hu, Chiyi
Florescu, Silvia
Haro, Josep Maria
Lim, Carmen Cw
Kovess-Masfety, Viviane
Levinson, Daphna
Medina Mora, Maria Elena
Piazza, Marina
Piotrowski, Patryk
Posada-Villa, Jose
Khalaf, Mohammad Salih
Ten Have, Margreet
Xavier, Miguel
Scott, Kate M #
Issue Date: Jan-2015
Publisher: Churchill Livingstone
Series Title: The Journal of Pain vol:16 issue:1 pages:42-52
Article number: S1526-5900(14)00973-0
Abstract: Although there is a significant association between pre-existing depression and later onset of chronic headache, the extent to which other pre-existing mental disorders are associated with subsequent onset of headache in the general population is not known. Also unknown is the extent to which these associations vary by gender or by life course. We report global data from the WHO's World Mental Health surveys (N=52,095), in which, by means of the Composite International Diagnostic Interview-3.0 (CIDI-3.0), 16 DSM-IV mental disorders were retrospectively assessed in terms of lifetime prevalence and age-of-onset. Frequent or severe headaches were assessed using self-reports. After adjustment for covariates, survival models showed a moderate but consistent association between pre-existing mood (ORs 1.3-1.4), anxiety (ORs 1.2-1.7), and impulse-control disorders (ORs 1.7-1.9) and the subsequent onset of headache. We also found a dose-response relationship between the number of pre-existing mental disorders and subsequent headache onset (OR ranging between 1.9 for 1 up to 3.4 for 5+ pre-existing mental disorders). Our findings suggest a consistent and pervasive relationship between a wide range of pre-existing mental disorders and the subsequent onset of headaches. This highlights the importance of assessing a broad range of mental disorders, not just depression, as specific risk factors for the subsequent onset of frequent or severe headaches.
ISSN: 1526-5900
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Research Group Psychiatry
× corresponding author
# (joint) last author

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