Microporous and mesoporous materials vol:44 pages:477-482
Pt-Sn/MCM-41 reduction catalysts were prepared by a two-step impregnation procedure. The effect of the Sn content was evaluated in the liquid-phase hydrogen transfer reduction of an enone prostaglandin intermediate. Results indicate that up to a Sn/Pt atomic ratio of 3.3 increasing amounts of Sn favor the formation of the allylic alcohol. The reaction also displays mode rate diastereoselectivity. On the other hand, the Pt/MCM-41 catalyst produces the saturated ketone as the main reaction product. (C) 2001 Elsevier Science B.V. All rights reserved.