Title: Inhaled medication and inhalation devices for lung disease in patients with cystic fibrosis: A European consensus
Authors: Heijerman, Harry ×
Westerman, Elsbeth
Conway, Steven
Touw, Daan
Döring, Gerd
Consensus working group #
Issue Date: Sep-2009
Series Title: Journal of Cystic Fibrosis vol:8 issue:5 pages:295-315
Article number: 10.1016/j.jcf.2009.04.005
Abstract: In cystic fibrosis inhalation of drugs for the treatment of CF related lung disease has been proven to be highly effective. Consequently, an increasing number of drugs and devices have been developed for CF lung disease or are currently under development. In this European consensus document we review the current status of inhaled medication in CF, including the mechanisms of action of the various drugs, their modes of administration and indications, their effects on lung function, exacerbation rates, survival and quality of life, as well as side effects. Specifically we address antibiotics, mucolytics/mucous mobilizers, anti-inflammatory drugs, bronchodilators and combinations of solutions. Additionally, we review the current knowledge on devices for inhalation therapy with regard to optimal particle sizes and characteristics of wet nebulisers, dry powder and metered dose inhalers. Finally, we address the subject of testing new devices before market introduction.
ISSN: 1569-1993
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pediatric Pulmonology Section (-)
Organ Systems (+)
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science