Title: From intestinal permeability to dysmotility: the biobreeding rat as a model for functional gastrointestinal disorders
Authors: Vanuytsel, Tim
Vanormelingen, Christophe
Vanheel, Hanne
Masaoka, Tatsuhiro
Salim Rasoel, Shadea
Tóth, Joran
Houben, Els
Verbeke, Kristin
De Hertogh, Gert
Vanden Berghe, Pieter
Tack, Jan ×
Farré, Ricard #
Issue Date: 2014
Publisher: Public Library of Sciene
Series Title: PLoS One vol:9 issue:10 pages:e111132
Article number: 10.1371/journal.pone.0111132
Abstract: Impaired intestinal barrier function, low-grade inflammation and altered neuronal control are reported in functional gastrointestinal disorders. However, the sequence of and causal relation between these events is unclear, necessitating a spontaneous animal model. The aim of this study was to describe the natural history of intestinal permeability, mucosal and neuromuscular inflammation and nitrergic motor neuron function during the lifetime of the BioBreeding (BB) rat.
ISSN: 1932-6203
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Translational Research in GastroIntestinal Disorders
Translational Cell & Tissue Research
× corresponding author
# (joint) last author

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