Title: Organophosphorus-catalyzed diaza-Wittig reaction: application to the synthesis of pyridazines
Authors: Bel Abed, Hassen
Mammoliti, Oscar
Bande, Omprakash
Van Lommen, Guy
Herdewijn, Piet # ×
Issue Date: 2014
Series Title: ORGANIC & BIOMOLECULAR CHEMISTRY vol:12 issue:36 pages:7159-7166
Abstract: The elaboration of the first organophosphorus-catalyzed diaza-Wittig reaction is reported. This catalytic reaction is applied to the synthesis of substituted pyridazine and phthalazine derivatives bearing electron-withdrawing groups with good to excellent yields from substrates containing a diazo functionality as the starting material and a phospholene oxide as the catalyst.
ISSN: 1477-0520
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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