Title: Argon: systematic review on neuro- and organoprotective properties of an "inert" gas
Authors: Höllig, Anke ×
Schug, Anita
Fahlenkamp, Astrid V.
Rossaint, Rolf
Coburn, Mark
Rex, Steffen
Neyrinck, Arne
Argon Organo-Protective Network (AON) #
Issue Date: 2014
Publisher: MDPI
Series Title: International Journal of Molecular Sciences vol:15 pages:18175-18196
Article number: 10.3390/ijms151018175
Abstract: Argon belongs to the group of noble gases, which are regarded as chemically inert. Astonishingly some of these gases exert biological properties and during the last decades more and more reports demonstrated neuroprotective and organoprotective effects. Recent studies predominately use in vivo or in vitro models for ischemic pathologies to investigate the effect of argon treatment. Promising data has been published concerning pathologies like cerebral ischemia, traumatic brain injury and hypoxic ischemic encephalopathy. However, models applied and administration of the therapeutic gas vary. Here we provide a systematic review to summarize the available data on argon's neuro- and organoprotective effects and discuss its possible mechanism of action. We aim to provide a summary to allow further studies with a more homogeneous setting to investigate possible clinical applications of argon.
ISSN: 1422-0067
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Anesthesiology and Algology
× corresponding author
# (joint) last author

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