Title: Intestinal epithelial vitamin D receptor deletion leads to defective autophagy in colitis
Authors: Wu, Shaoping
Zhang, Yong-Guo
Lu, Rong
Xia, Yinglin
Zhou, David
Petrof, Elaine O
Claud, Erika C
Chen, Di
Chang, Eugene B
Carmeliet, Geert
Sun, Jun # ×
Issue Date: Jul-2015
Publisher: BMJ Publishing Group
Series Title: Gut vol:64 issue:7 pages:1082-94
Article number: 25080448
Abstract: Vitamin D and the vitamin D receptor (VDR) appear to be important immunological regulators of inflammatory bowel diseases (IBD). Defective autophagy has also been implicated in IBD, where interestingly, polymorphisms of genes such as ATG16L1 have been associated with increased risk. Although vitamin D, the microbiome and autophagy are all involved in pathogenesis of IBD, it remains unclear whether these processes are related or function independently.
ISSN: 0017-5749
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Clinical and Experimental Endocrinology
× corresponding author
# (joint) last author

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