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Title: Evaluation of PET radioligands for in vivo visualization of phosphodiesterase 5 (PDE5)
Authors: Chekol, Rufael ×
Gheysens, Olivier
Cleynhens, Jan
Pokreisz, Peter
Vanhoof, Greet
Ahamed, Muneer
Janssens, Stefan
Verbruggen, Alfons
Bormans, Guy #
Issue Date: Feb-2014
Publisher: Pergamon Press
Series Title: Nuclear Medicine and Biology vol:41 issue:2 pages:155-162
Article number: S0969-8051(13)00217-5
Abstract: The cyclic guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) is considered to play an important role in various etiologies such as pulmonary arterial hypertension (PAH) and chronic heart failure. This PDE5 modulation represents an important prognostic and/or therapeutic target; however, there is currently no method to non-invasively evaluate the PDE5 expression levels in vivo.
ISSN: 0969-8051
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiopharmacy
× corresponding author
# (joint) last author

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