Title: Synthesis of 4-substituted-1,2,3-triazole carbanucleoside analogues of ribavirin via click chemistry
Authors: Pérez-Castro, Isabel ×
Caamaño, Olga
Fernández, Franco
García, Marcos D
López, Carmen
De Clercq, Erik #
Issue Date: Dec-2007
Series Title: Organic & biomolecular chemistry vol:5 issue:23 pages:3805-13
Abstract: The synthesis and biological evaluation as antiviral agents of a series of racemic 4-aryl-1,2,3-triazolo-2',3'-dideoxy-2'-iodocarbanucleosides and 4-aryl-1,2,3-triazolo-2',3'-dideoxy-2',3'-didehydrocarbanucleosides is presented. These compounds were produced using a click chemistry approach, with the iodoazide 13a as the key intermediary.
ISSN: 1477-0520
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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