Title: Capsid (CA) protein as a novel drug target: recent progress in the research of HIV-1 CA inhibitors
Authors: Zhang, Jiyan ×
Liu, Xinyong
De Clercq, Erik #
Issue Date: Apr-2009
Series Title: Mini reviews in medicinal chemistry vol:9 issue:4 pages:510-8
Abstract: The capsid (CA) protein is the major structural component of HIV-1 and plays a key role in the regulation of viral life cycle. Inhibition of CA will affect the viral assembly and budding processes, causing decreased viral infectivity. This review describes the structure and function of the HIV-1 CA and latest progress in the discovery of HIV-1 CA inhibitors.
ISSN: 1389-5575
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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