A meta-analysis of immunogenetic Case-Control Association Studies in irritable bowel syndrome
Czogalla, B × Schmitteckert, S Houghton, L A Sayuk, G S Camilleri, M Olivo-Diaz, A Spiller, R Wouters, Mira Boeckxstaens, Guy Lorenzo Bermejo, J Niesler, B #
Neurogastroenterology and Motility vol:27 issue:5 pages:717-27
To date, genetic-association studies of single nucleotide polymorphisms (SNP) in selected candidate genes with the symptom phenotype of irritable bowel syndrome (IBS) have typically involved hundreds to 2000 patients. SNPs in immune-related genes, such as cytokine and cytokine receptor encoding genes, have been reported to associate with IBS risk.