Title: Musculoskeletal disorders in chronic obstructive pulmonary disease
Authors: Cielen, Nele ×
Maes, Karen
Gayan-Ramirez, Ghislaine #
Issue Date: 2014
Publisher: Hindawi Publishing Corporation
Series Title: BioMed Research International vol:2014 pages:965764
Article number: 10.1155/2014/965764
Abstract: Chronic obstructive pulmonary disease (COPD) is a lung disease characterized by airway obstruction and inflammation but also accompanied by several extrapulmonary consequences, such as skeletal muscle weakness and osteoporosis. Skeletal muscle weakness is of major concern, since it leads to poor functional capacity, impaired health status, increased healthcare utilization, and even mortality, independently of lung function. Osteoporosis leads to fractures and is associated with increased mortality, functional decline, loss of quality of life, and need for institutionalization. Therefore, the presence of the combination of these comorbidities will have a negative impact on daily life in patients with COPD. In this review, we will focus on these two comorbidities, their prevalence in COPD, combined risk factors, and pathogenesis. We will try to prove the clustering of these comorbidities and discuss possible preventive or therapeutic strategies.
ISSN: 2314-6133
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Pneumology
× corresponding author
# (joint) last author

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