Title: TRP channels in the skin
Authors: Tóth, Balázs István
Oláh, Attila
Szöllősi, Attila Gábor
Bíró, Tamás # ×
Issue Date: May-2014
Series Title: British journal of pharmacology vol:171 issue:10 pages:2568-2581
Article number: 10.1111/bph.12569
Abstract: Emerging evidence suggests that transient receptor potential (TRP) ion channels not only act as 'polymodal cellular sensors' on sensory neurons but are also functionally expressed by a multitude of non-neuronal cell types. This is especially true in the skin, one of the largest organs of the body, where they appear to be critically involved in regulating various cutaneous functions both under physiological and pathophysiological conditions. In this review, we focus on introducing the roles of several cutaneous TRP channels in the regulation of the skin barrier, skin cell proliferation and differentiation, and immune functions. Moreover, we also describe the putative involvement of several TRP channels in the development of certain skin diseases and identify future TRP channel-targeted therapeutic opportunities.
ISSN: 0007-1188
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Ion Channel Research
× corresponding author
# (joint) last author

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