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Title: Synthetic Protocol toward Fused Pyrazolone Derivatives via a Michael Addition and Reductive Ring Closing Strategy
Authors: Parekh, Nikita
Thomas, Joice
John, Jubi
Kusurkar, Radhika
De Borggraeve, Wim M
Dehaen, Wim # ×
Issue Date: 2014
Publisher: AMER CHEMICAL SOC
Series Title: JOURNAL OF ORGANIC CHEMISTRY vol:79 issue:11 pages:5338-5344
Abstract: A new class of pyrazolo[3,4-c]pyridine-3,7-dione and pyrazolo[3,4-d]azepine-3,7-dione scaffolds was synthesized via a Michael addition and reductive cyclization strategy. These fused heterocycles were accessed from simple starting materials such as nitroolefins and 3-ethoxycarbonyl-(methylene)pyrazoline-5-one. The pyrazolo-fused heterocycles were obtained in good overall yields.
ISSN: 0022-3263
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Molecular Design and Synthesis
× corresponding author
# (joint) last author

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