Title: Synthesis and biological evaluation of carbon-11 and fluorine-18 labeled tracers for in vivo visualization of PDE10A
Authors: Ooms, Maarten
Celen, Sofie
Koole, Michel
Langlois, Xavier
Schmidt, Mark
De Angelis, Meri
Andrés, José Ignacio
Verbruggen, Alfons
Van Laere, Koen
Bormans, Guy # ×
Issue Date: Sep-2014
Publisher: Pergamon Press
Series Title: Nuclear Medicine and Biology vol:41 issue:8 pages:695-704
Article number: 10.1016/j.nucmedbio.2014.05.138
Abstract: In vivo visualization of PDE10A using PET provides a tool to evaluate the role of PDE10A in various neuropsychiatric diseases and can also be useful in the clinical evaluation of PDE10A inhibitor drug candidates. We evaluated several carbon-11 and fluorine-18 labeled PDE10A inhibitors as potential PDE10A PET radioligands.
ISSN: 0969-8051
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Radiopharmaceutical Research
Nuclear Medicine & Molecular Imaging
× corresponding author
# (joint) last author

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