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Title: BRCA1 gene promoter methylation status in high-grade serous ovarian cancer patients - A study of the tumour Bank ovarian cancer (TOC) and ovarian cancer diagnosis consortium (OVCAD)
Authors: Ruscito, I ×
Vasconcelos, I
Gellhaus, K
Schwachula, T
Bellati, F
Zeillinger, R
Benedetti-Panici, P
Vergote, Ignace
Mahner, S
Cacsire-Tong, D
Concin, N
Darb-Esfahani, S
Lambrechts, S
Sehouli, J
Olek, S
Braicu, E I #
Issue Date: Aug-2014
Publisher: Pergamon
Series Title: European Journal of Cancer vol:50 issue:12 pages:2090-8
Article number: S0959-8049(14)00649-2
Abstract: Mutations in BRCA1/2 genes are involved in the pathogenesis of breast and ovarian cancer. Inactivation of these genes can also be mediated by hypermethylation of CpGs in the promoter regions. Aim of this study was to analyse the clinical impact of BRCA1 promoter gene methylation status in a homogenous cohort of high-grade serous ovarian cancer (HGSOC) patients.
ISSN: 0959-8049
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Gynaecological Oncology
Research Unit KU Leuven Centre for IT & IP Law (CiTiP)
× corresponding author
# (joint) last author

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