Title: Antiviral drug-resistance typing reveals compartmentalization and dynamics of acyclovir-resistant herpes simplex virus type-2 (HSV-2) in a case of neonatal herpes
Authors: Bache, Manon ×
Andrei, Graciela
Bindl, Lutz
Bofferding, Léon
Bottu, Jean
Géron, Christine
Neuhäuser, Christoph
Gillemot, Sarah
Fiten, Pierre
Opdenakker, Ghislain
Snoeck, Robert #
Issue Date: Jun-2014
Publisher: Oxford University Press
Series Title: Journal of the Pediatric Infectious Diseases Society vol:3 issue:2 pages:e24-e27
Abstract: A neonate suffering from herpes simplex virus type 2 disease with central nervous system involvement developed an early recurrence under acyclovir therapy. Isolates from the cerebrospinal fluid and skin lesions were acyclovir resistant, while viruses from blood and trachea were not. Acyclovir combined with foscavir followed by long-term suppressive acyclovir therapy supported normal neurological development.
ISSN: 2048-7193
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Immunobiology (Rega Institute)
Laboratory of Virology and Chemotherapy (Rega Institute)
× corresponding author
# (joint) last author

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