Title: Carcinoid heart disease. Case report and review of the literature
Authors: Robyns, Tomas ×
Vankelecom, Bart #
Issue Date: 2011
Publisher: Nederlandstalige Medische Faculteiten in België
Series Title: Tijdschrift voor Geneeskunde vol:67 issue:16 pages:765-772
Abstract: Carcinoid heart disease is a complication of a rare
syndrome caused by systemic spread of vaso-active
substances from tumoral metastases. Starting from an
interesting clinical case, we focus on histology, pathogenesis, diagnosis and treatment of carcinoid heart
disease. The pathogenesis is still poorly understood.
Historically serotonin was considered to be the causing
agent of fibrosis seen in carcinoid heart disease. Recently there has been a focus on other vaso-active substances and on growth factors. The combination of clinical findings, biochemistry and echocardiography is needed to achieve a diagnosis and prognosis. The current treatment mainly consists of somatostatine analogues and in selected cases valve surgery.
ISSN: 0371-683X
Publication status: published
KU Leuven publication type: AT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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