Title: Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial
Authors: Krop, Ian E ×
Kim, Sung-Bae
González-Martín, Antonio
Lorusso, Patricia M
Ferrero, Jean-Marc
Smitt, Melanie
Yu, Ron
Leung, Abraham C F
Wildiers, Hans
on behalf of the TH3RESA study collaborators #
Issue Date: Jun-2014
Publisher: Lancet Pub. Group
Series Title: The Lancet Oncology vol:15 issue:7 pages:689-99
Article number: S1470-2045(14)70178-0
Abstract: Patients with progressive disease after two or more HER2-directed regimens for recurrent or metastatic breast cancer have few effective therapeutic options. We aimed to compare trastuzumab emtansine, an antibody-drug conjugate comprising the cytotoxic agent DM1 linked to trastuzumab, with treatment of physician's choice in this population of patients.
ISSN: 1470-2045
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Experimental Oncology
× corresponding author
# (joint) last author

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