Title: The first caprine rotavirus detected in Argentina displays genomic features resembling virus strains infecting members of the Bovidae and Camelidae
Authors: Louge Uriarte, Enrique L ×
Badaracco, Alejandra
Matthijnssens, Jelle
Zeller, Mark
Heylen, Elisabeth
Manazza, Jorge
Miño, Samuel
Van Ranst, Marc
Odeón, Anselmo
Parreño, Viviana #
Issue Date: Jun-2014
Publisher: Elsevier Scientific Pub. Co.
Series Title: Veterinary Microbiology vol:171 issue:1-2 pages:189-97
Article number: S0378-1135(14)00163-1
Abstract: Rotavirus group A (RVA) is a major cause of diarrhea in humans and young animals including small ruminants. The purpose of this study was to identify RVA in dairy goat kids, and to characterize the complete genomic constellation and genetic relatedness with other RVA strains. Four out of twenty fecal samples from diarrheic and non-diarrheic goat kids were positive for RVA by ELISA. A representative sample was selected for further genome analyses. The RVA strain RVA/Goat-wt/ARG/0040/2011/G8P[1] displayed the following genomic constellation: G8-P[1]-I2-R5-C2-M2-A3-N2-T6-E12-H3, reminiscent to guanaco and other bovine-like RVA strains detected in Argentina. Phylogenetic analyses revealed that most of the genome segments had a rather close relatedness with RVA strains typically obtained from cattle, sheep, South American camelids and goats. Interestingly, strain 0040 possessed the R5 and E12 genotypes which have up to date only been found in different animal species from Argentina. Overall, these findings suggest that strain 0040 could represent a typical goat RVA genome constellation similar to those previously found in other animal species within the order Artiodactyla.
ISSN: 0378-1135
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Laboratory of Clinical and Epidemiological Virology (Rega Institute)
Department of Health and Technology - UC Leuven
× corresponding author
# (joint) last author

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