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Title: Quantitative phylogenetic assessment of microbial communities in diverse environments
Authors: von Mering, C ×
Hugenholtz, P
Raes, Jeroen
Tringe, S G
Doerks, T
Jensen, L J
Ward, N
Bork, P #
Issue Date: Feb-2007
Publisher: American Association for the Advancement of Science
Series Title: Science vol:315 issue:5815 pages:1126-1130
Abstract: The taxonomic composition of environmental communities is an important indicator of their ecology and function. We used a set of protein-coding marker genes, extracted from large-scale environmental shotgun sequencing data, to provide a more direct, quantitative, and accurate picture of community composition than that provided by traditional ribosomal RNA-based approaches depending on the polymerase chain reaction. Mapping marker genes from four diverse environmental data sets onto a reference species phylogeny shows that certain communities evolve faster than others. The method also enables determination of preferred habitats for entire microbial clades and provides evidence that such habitat preferences are often remarkably stable over time.
URI: 
ISSN: 0036-8075
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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