Title: Inferring transcriptional modules from ChIP-chip, motif and microarray data
Authors: Lemmens, Karen
Dhollander, Thomas
De Bie, Tijl
Monsieurs, Pieter
Engelen, Kristof
Smets, Bart
Winderickx, Joris
De Moor, Bart
Marchal, Kathleen # ×
Issue Date: 2006
Publisher: BioMed Central Ltd.
Series Title: Genome Biology vol:7 issue:5 pages:1-14
Article number: R37
Abstract: AB - 'ReMoDiscovery' is an intuitive algorithm to correlate regulatory programs with regulators and corresponding motifs to a set of co-expressed genes. It exploits in a concurrent way three independent data sources: ChIP-chip data, motif information and gene expression profiles. When compared to published module discovery algorithms, ReMoDiscovery is fast and easily tunable. We evaluated our method on yeast data, where it was shown to generate biologically meaningful findings and allowed the prediction of potential novel roles of transcriptional regulators
Description: 01
ISSN: 1465-6906
Publication status: published
KU Leuven publication type: IT
Appears in Collections:ESAT - STADIUS, Stadius Centre for Dynamical Systems, Signal Processing and Data Analytics
Centre of Microbial and Plant Genetics
Division of Mechatronics, Biostatistics and Sensors (MeBioS)
ESAT - ELECTA, Electrical Energy Computer Architectures
Electrical Engineering - miscellaneous
Laboratory for Functional Biology (-)
Molecular Physiology of Plants and Micro-organisms Section - miscellaneous
Quantitative Psychology and Individual Differences
× corresponding author
# (joint) last author

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