ITEM METADATA RECORD
Title: Functional divergence of proteins through frameshift mutations
Authors: Raes, Jeroen ×
Van de Peer, Yves #
Issue Date: Aug-2005
Publisher: ELSEVIER SCIENCE LONDON
Series Title: Trends in Genetics vol:21 issue:8 pages:428-431
Abstract: Frameshift mutations are generally considered to be deleterious and of little importance for the evolution of novel gene functions. However, by screening an exhaustive set of vertebrate gene families, we found that, when a second transcript encoding the original gene product compensates for this mutation, frameshift mutations can be retained for millions of years and enable new gene functions to be acquired.
URI: 
ISSN: 0168-9525
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Non-KU Leuven Association publications
× corresponding author
# (joint) last author

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