Inter- and Intra-individual Variability Following Intermittent Theta Burst Stimulation: Implications for Rehabilitation and Recovery
Hinder, Mark R × Goss, Emily L Fujiyama, Hak Canty, Alison J Garry, Michael I Rodger, Jennifer Summers, Jeffery J #
Elsevier Science Inc
Brain Stimulation vol:7 issue:3 pages:365-71
The continued refinement of non-invasive brain stimulation (NBS) techniques is indicative of promising clinical and rehabilitative interventions that are able to modulate cortical excitability. Intermittent theta burst stimulation (iTBS) is one such technique that can increase cortical excitability, purportedly via LTP-like mechanisms. While iTBS may have the capacity to promote recovery after neurological injury, and to combat cognitive and motor decline, recent reports observed highly variable effects across individuals, questioning the efficacy of iTBS as a clinical tool.