Title: A Core Invasiveness Gene Signature Reflects Epithelial-to-Mesenchymal Transition but Not Metastatic Potential in Breast Cancer Cell Lines and Tissue Samples
Authors: Marsan, Melike ×
Van den Eynden, Gert
Limame, Ridha
Neven, Patrick
Hauspy, Jan
Van Dam, Peter A
Vergote, Ignace
Dirix, Luc Y
Vermeulen, Peter B
Van Laere, Steven #
Issue Date: 21-Feb-2014
Publisher: Public Library of Sciene
Series Title: PLoS One vol:9 issue:2 pages:e89262
Article number: 10.1371/journal.pone.0089262
Abstract: Metastases remain the primary cause of cancer-related death. The acquisition of invasive tumour cell behaviour is thought to be a cornerstone of the metastatic cascade. Therefore, gene signatures related to invasiveness could aid in stratifying patients according to their prognostic profile. In the present study we aimed at identifying an invasiveness gene signature and investigated its biological relevance in breast cancer.
ISSN: 1932-6203
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Gynaecological Oncology
× corresponding author
# (joint) last author

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