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Title: Can extracapsular lymph node involvement be a tool to fine-tune pN1 for adenocarcinoma of the oesophagus and gastro-oesophageal junction in the Union Internationale contre le Cancer (UICC) TNM 7th edition?
Authors: Nafteux, Philippe ×
Lerut, Toni
De Hertogh, Gert
Moons, Johnny
Coosemans, Willy
Decker, Georges
Van Veer, Hans
De Leyn, Paul #
Issue Date: Jun-2014
Publisher: Elsevier Science
Series Title: European Journal of Cardio-Thoracic Surgery vol:45 issue:6 pages:1001-1010
Abstract: The current (7th) International Union Against Cancer (UICC) pN staging system is based on the number of positive lymph nodes but does not take into consideration the characteristics of the metastatic lymph nodes itself. In particular, it has been suggested that tumour penetration beyond the lymph node capsule in metastatic lymph nodes, which is also called extracapsular lymph node involvement, has a prognostic impact. The aim of the current study was to assess the prognostic value of extracapsular (EC) and intracapsular (IC) lymph node involvement (LNI) in adenocarcinoma of the oesophagus and gastro-oesophageal junction (GOJ) and to assess its potential impact on the 7th edition of the UICC TNM manual.
URI: 
ISSN: 1010-7940
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Thoracic Surgery
× corresponding author
# (joint) last author

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