ITEM METADATA RECORD
Title: Hydroxy fatty acids for the delivery of dideoxynucleosides as anti-HIV agents
Authors: Gangadhara, Kishore Lingam
Lescrinier, Eveline
Pannecouque, Christophe
Herdewijn, Piet # ×
Issue Date: Feb-2014
Publisher: Pergamon Press
Series Title: Bioorganic & Medicinal Chemistry Letters vol:24 issue:3 pages:817-20
Abstract: A series of α- and β-carboxylated phospholipid prodrugs of dideoxy nucleosides have been synthesized and evaluated against HIV. An increase in biological effect with a factor of 500 has only been observed for the adenine nucleoside, which suggests that this prodrug approach is base specific.
URI: 
ISSN: 0960-894X
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Medicinal Chemistry (Rega Institute)
× corresponding author
# (joint) last author

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