Title: The SafeBoosC phase II randomised clinical trial: a treatment guideline for targeted near-infrared-derived cerebral tissue oxygenation versus standard treatment in extremely preterm infants
Authors: Pellicer, Adelina ×
Greisen, Gorm
Benders, Manon
Claris, Olivier
Dempsey, Eugene
Fumagalli, Monica
Gluud, Christian
Hagmann, Cornelia
Hellström-Westas, Lena
Hyttel-Sorensen, Simon
Lemmers, Petra
Naulaers, Gunnar
Pichler, Gerhard
Roll, Claudia
van Bel, Frank
van Oeveren, Wim
Skoog, Maria
Wolf, Martin
Austin, Topun #
Issue Date: 2013
Publisher: S. Karger AG
Series Title: Neonatology vol:104 issue:3 pages:171-8
Article number: 10.1159/000351346
Abstract: Near-infrared spectroscopy-derived regional tissue oxygen saturation of haemoglobin (rStO2) reflects venous oxygen saturation. If cerebral metabolism is stable, rStO2 can be used as an estimate of cerebral oxygen delivery. The SafeBoosC phase II randomised clinical trial hypothesises that the burden of hypo- and hyperoxia can be reduced by the combined use of close monitoring of the cerebral rStO2 and a treatment guideline to correct deviations in rStO2 outside a predefined target range.
ISSN: 1661-7800
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Organ Systems (+)
× corresponding author
# (joint) last author

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