Clinical use of cerebral oximetry in extremely preterm infants is feasible
Hyttel-Sørensen, Simon × Austin, Topun van Bel, Frank Benders, Manon Claris, Olivier Dempsey, Eugene M Fumagalli, Monica Gluud, Christian Hagmann, Cornelia Hellström-Westas, Lena Lemmers, Petra Naulaers, Gunnar van Oeveren, Wim Pellicer, Adelina Pichler, Gerhard Roll, Claudia Støy, Lina Saem Wolf, Martin Greisen, Gorm #
Danish Medical Association
Danish Medical Journal vol:60 issue:1 pages:A4533
The research programme Safeguarding the Brains of our smallest Children (SafeBoosC) aims to test the benefits and harms of cerebral near-infrared spectroscopy (NIRS) oximetry in infants born before 28 weeks of gestation. In a phase II trial, infants will be randomised to visible cerebral NIRS oximetry with pre-specified treatment guidelines compared to standard care with blinded NIRS-monitoring. The primary outcome is duration multiplied with the extent outside the normal range of regional tissue oxygen saturation of haemoglobin (rStO2) of 55 to 85% in percentage hours (burden). This study was a pilot of the Visible -Oximetry Group.