Title: A phase II randomized clinical trial on cerebral near-infrared spectroscopy plus a treatment guideline versus treatment as usual for extremely preterm infants during the first three days of life (SafeBoosC): study protocol for a randomized controlled trial
Authors: Hyttel-Sorensen, Simon ×
Austin, Topun
van Bel, Frank
Benders, Manon
Claris, Olivier
Dempsey, Eugene
Fumagalli, Monica
Greisen, Gorm
Grevstad, Berit
Hagmann, Cornelia
Hellström-Westas, Lena
Lemmers, Petra
Lindschou, Jane
Naulaers, Gunnar
van Oeveren, Wim
Pellicer, Adelina
Pichler, Gerhard
Roll, Claudia
Skoog, Maria
Winkel, Per
Wolf, Martin
Gluud, Christian #
Issue Date: 2013
Publisher: BioMed Central
Series Title: Trials vol:14 pages:120-125
Article number: 10.1186/1745-6215-14-120
Abstract: Every year in Europe about 25,000 infants are born extremely preterm. These infants have a 20% mortality rate, and 25% of survivors have severe long-term cerebral impairment. Preventative measures are key to reduce mortality and morbidity in an extremely preterm population. The primary objective of the SafeBoosC phase II trial is to examine if it is possible to stabilize the cerebral oxygenation of extremely preterm infants during the first 72 hours of life through the application of cerebral near-infrared spectroscopy (NIRS) oximetry and implementation of an clinical treatment guideline based on intervention thresholds of cerebral regional tissue saturation rStO2.
ISSN: 1745-6215
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Organ Systems (+)
× corresponding author
# (joint) last author

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