Title: Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium
Authors: Altmäe, Signe ×
Esteban, Francisco J
Stavreus-Evers, Anneli
Simón, Carlos
Giudice, Linda
Lessey, Bruce A
Horcajadas, Jose A
Macklon, Nick S
D'Hooghe, Thomas
Campoy, Cristina
Fauser, Bart C
Salamonsen, Lois A
Salumets, Andres #
Issue Date: 2014
Publisher: Published for the European Society of Human Reproduction and Embryology by Oxford University Press
Series Title: Human Reproduction Update vol:20 issue:1 pages:12-28
Article number: 10.1093/humupd/dmt048
Abstract: 'Omics' high-throughput analyses, including genomics, epigenomics, transcriptomics, proteomics and metabolomics, are widely applied in human endometrial studies. Analysis of endometrial transcriptome patterns in physiological and pathophysiological conditions has been to date the most commonly applied 'omics' technique in human endometrium. As the technologies improve, proteomics holds the next big promise for this field. The 'omics' technologies have undoubtedly advanced our knowledge of human endometrium in relation to fertility and different diseases. Nevertheless, the challenges arising from the vast amount of data generated and the broad variation of 'omics' profiling according to different environments and stimuli make it difficult to assess the validity, reproducibility and interpretation of such 'omics' data. With the expansion of 'omics' analyses in the study of the endometrium, there is a growing need to develop guidelines for the design of studies, and the analysis and interpretation of 'omics' data.
ISSN: 1355-4786
Publication status: published
KU Leuven publication type: IT
Appears in Collections:Organ Systems (+)
× corresponding author
# (joint) last author

Files in This Item:

There are no files associated with this item.

Request a copy


All items in Lirias are protected by copyright, with all rights reserved.

© Web of science