Effect of biologic treatments on growth in children with juvenile idiopathic arthritis
Uettwiller, Florence × Perlbarg, Julie Pinto, Graziella Bader-Meunier, Brigitte Mouy, Richard Compeyrot-Lacassagne, Sandrine Melki, Isabelle Wouters, Carine Prieur, Anne-Marie Landais, Paul Polak, Michel Quartier, Pierre #
Journal of Rheumatology Pub. Co.
Journal of Rheumatology vol:41 issue:1 pages:128-35
Growth retardation is a frequent complication of severe juvenile idiopathic arthritis (JIA). Biologic treatments may improve growth velocity by controlling systemic inflammation and reducing corticosteroids. Our goals were to compare growth velocity before and after the onset of biologic therapy and to determine whether the JIA subtype, the use of steroids, the requirement of one or several biologic agents, or the disease activity influenced growth velocity.